Triple negative breast cancer (TNBC) is a breast cancer subtype, which is found in 10-20% of all breast cancer diagnoses each year. The name originates from tumors found in the breast that are estrogen receptor-negative, progesterone receptor-negative, and human epidermal growth factor receptor 2-negative. In other words, TNBC tumors do not exhibit any of these three receptors. Although these tumors do not respond to receptor-specific treatments, they are typically responsive to chemotherapy.
